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Does chametz apply only to what is eaten orally or to any type of nutrition / food regardless of how it is ingested?

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  • You're not aloud to benefit from chametz on Pesach, so... assuming you're not talking about pikuach nefesh I think it's pretty clear that you couldn't use chametzdich IVs
    – Daniel
    Commented Mar 22, 2015 at 1:37

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There are really two parts to your question. One is: do the rules of Chametz apply regardless how it is ingested?

http://www.star-k.org/kashrus/kk-mitzvos-cosmetics.htm

On Pesach, one may not consume, own or derive benefit from items that contain derivatives of the chameishes minei dagan - wheat, barley, spelt, oats, and rye.

The second part of your question is regarding an IV, where often the one who gets such nutrition is sick. There it would depend on availability of non-Chametz options, how sick, etc. A question for each individual to his local rabbi.

See also from CRC-Chicago that says that most intravenous does not contain Chometz and even if it did one who is incapacitated is allowed to take it.

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