This question is a part of a series on "death hastening".
As I understand, the Treyfah condition in humans is when one is destined to die in the foreseeable future (12 months?) with a high degree of certainty (see also WIKI).
I presume the advances in technology and medicine had shaken some of those definitions.
What medical conditions are considered Treyfah nowadays? And what had changed from the classical Rabbinical knowledge?