In Vayishlach (Ber. 36:10) Eisav has a son named Reu'el. While the meanings of/reasons for the names of those in Eisav's line are not provided, it seems to me that this name sticks out because it includes the theophoric -el construction which is often associated with Hashem (cf Yishma'el, Yisra'el, P'ni'el), and yet it was used in the family of Eisav, not known for its relationship with Hashem.
[In the case of the (grand)father-in-law of Moshe, it could be said that it presages his connection to Hashem as per https://en.wikipedia.org/wiki/Reuel and it fits in with the explanation for other of his names as per https://www.jewishvirtuallibrary.org/jethro-2]
Are there are commentators which explain why that name might have been used for that particular child of Eisav (does it predict or describe anything in his character which sets him apart)?