I have a severe progressive neurological disease and it's exceptionally painful. Current medical technology unfortunately is not able to provide much in the way of treatment or relief. Everyday things like eating, drinking, walking up the stairs, and doing lot of things varies from mildly to severely painful in addition to extremely fatiguing. And this often gets to the point that regular every day life is exceptionally depressing.
This has meant that things like dovening, putting on teffilin, going to shul, and lots of other mitsvos are extremely hard and painful. A long time ago I asked my Rebbe in yeshiva about this and he told me basically "tough luck". He wasn't empathetic at all.
However recently I was perusing Stack Exchange and I came upon a radical idea (from Alex) that sometimes there may be peturim / heterim for various things. The suggestion there varied from just minhogim to even some derebonons. See here: https://judaism.stackexchange.com/a/95530/17540
Additionally, is there a mokor to be excessively makel? I'm not talking about eating treif. But I am wondering if one can one look for the most makel shitoh among the poskim in a situation where doing something is very painful and/or exhausting. For example, if there is a single yaish omrim in the Taz, could I just rely on that even in a d'oriaso l'hokel when there is a huge amount of pain involved.
And more radically, are they times when for a d'rabonnon one can be potur l'gamrei? Perhaps the mitzvoh of arbah minnim could be done super quickly because the mitsvoh d'oraiso (IIRC) according to most rishonim is to just quickly hold the minim together for a short period of time.