For Birkat Hatora, writing is as speaking (SA OC 47,3): it is not allowed to write Divre Tora before Birkat Hatora.
- If someone ask you a question when you are davening, can you write an answer or is it a prohibited interruption as speaking?
- If someone want your signing for some reason, can you sign of is it an interruption as speaking, or is it a simple automatic movement of the hand?
Writing is not the same "instrument" than speaking which is used in Tefila, so the interruption is less perceptible. If we were praying by writing, to write something else would be surely an interruption.
May be that speaking and writing are equivalent from one point of view: they are not Devarim Shebalev, they are externalization of the thinking which originate from heart (Devarim Shebalev).
One a other hand, as it is possible to think somewhat else when in middle of prayer, it is possible to read an book in middle of prayer, and to enlight a statement on the book. It is also possible to write "Yes, No, Perhaps". So writing does not interrupt the flux of the speak.
One other side of the question is, following Rabenu Tam (Tosfot, Brachot 21b) who stated that without action of speaking, if you are hearing Kadish and Kedusha in middle of your prayer, it is an interruption because Shomea Keone. When you are writing, despite that you are not affiliated to an objective speaking, you are are affiliated to a speaking equivalent, and the lack of technical obstruction of the tfila speaking doesn't lead to a leniency.
I search an answer with a bit of moisture of lomdut.