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After eating food or drinking beverage, we say a blessing; however, this is only the case if some minimum amount of food or beverage has been consumed.
Likewise, after going to the bathroom, we say a blessing. Is this blessing also dependent on the quantity of the waste released?
There is no minimum amount below which it is not considered "going to the bathroom" for the sake of making a blessing. The Shulchan Arukh addresses this question explicitly:
אֵין שִׁעוּר לְהַשְׁתִּין מַיִם כִּי אֲפִלּוּ לְטִפָּה אַחַת חַיָּב לְבָרֵךְ, שֶׁאִם יִסָתֵם הַנֶּקֶב מִלְּהוֹצִיא הַטִּפָּה הַהִיא הָיָה קָשֶׁה לוֹ וְחַיָּב לְהוֹדוֹת:
There is no specific amount of urinating required, because even if one urinates a single drop one must bless ["who created man/Asher Yatzar"], because one's opening may have been blocked from urinating that drop and so it may have been difficult for him, and so he is required to give thanks.
So if even a drop of urine is released, you should make the asher yatzar blessing.
