Who knows two hundred sixteen?
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Exodus 14:19-21 are three consecutive verses of 72 letters each (totaling 216), from which Kabbalistic works extract 72 Divine names, each of three letters.
It is also the gematria of the words גבורה (strictness, severity) and אריה (lion), and of three times חסד (kindness, expansiveness). The connection: Divine חסד has to be channeled through גבורה for it to not overwhelm us. (R' Schneur Zalman of Liadi, Likkutei Torah, Devarim 13b ff)
According to official figures for the year 1870, there were in the nine northwestern provinces [of Russia] a total of 216 Jewish farming settlements, covering over 90,000 acres and comprising a population of 34,475.
"Agricultural Activities of the Jews in America", Leonard G. Robinson, 1912.
The Jewish calendar consists of 12 months annually. An extra leap month of 30 days is added every 2 or 3 years (7 leap months in 19 years) for a total of 235 lunar months in 19 years. This 19-year cycle is called the Metonic cycle and results in the 19 Jewish years approximating 19 solar years.
The Jewish holidays are always in the same season and vary by less than a month in the solar calendar. However, the approximation is not exact, and the average Jewish year is 6-7 minutes longer than the average solar year. As a result, the Jewish calendar is one day longer over approximately every 216 years. This causes a calendar drift where the holidays and seasons are gradually coming out later in the solar year.