By law
Ruach ra is not to touch orifices or food to remove it (completely) you need to use water
To say a brocho you only need to make your hands clean, (better with water, not only fingertips but whole fingers). If you slept with clothing your hands are considered clean for saying a brocho
But according to kabolo (Zohar)
you can not make a brocho (or walk 4 amos (if someone does he is hayav misa)) untill you remove the ruach raa
Shulchan aruch harav 1.7 says that a yiai shomaim should act according to the kabolo if possible
Some say to wash your mouth before saying a brocho
3 reasons to wash hands in the morning
From Shulchan aruch harav end of 4.3 and from 4.4
1 for prayer (to wash hands that were not watched for prayer (as by mincha and maariv too)
Needs to go the distance of 1 mil (~1km) out of his way to find water (or 4 mil on his way)
If no water can rub hands on something that cleans
2 to remover the ruach raa
Only with water
3 to clean them from the sweat they touched (to be able to say a brocho)
Do not need to go to find water
........
There are 2 versions of the first 4 simanim in the shulchan aruch harav so please follow the links for the right one