Due to the poor health of Lithuania's last Chief Rabbi, Rav Avraham Shapiro, and due to his death in 1943, many of the residents of Kovno Ghetto addressed their questions to Rav Shapiro's student, Rav Ephraim Oshry. After the Shoah, Rav Oshry returned to the ghetto and retrieved the copious texts that he had written, all of which he had buried in jars. He published the bulk of them in New York in 1959, under the title שאלות ותשובות ממעמקים (Responsa from the Depths). An abridged version exists in Hebrew and also in English, the latter being titled "Responsa from the Holocaust", but neither of these versions contains the halakhic argumentation that makes of the original a text worthy of being studied (rather than just one designed to elicit an emotional response).
The volumes published in 1959 are all available at HebrewBooks.org, but I cannot bear to read literature from a computer screen and the cost of privately publishing them is prohibitive. Does anybody know if the original Hebrew texts are available for purchase? My searches have yet to reveal any promising leads.