The children of Israel were commanded not to join with the Canaanites nor to learn their ways, lest they be led astray from the pure worship of Hashem into worshipping the idols of the nations. (Exodus 34:11-16, Joshua 23:7, Jeremiah 10:2)
Much of the world today does not worship statues or false deities but rather idols not associated with religions such as money, fame, and power. Along with the rest of creation, we were created for Hashem's glory (Isaiah 43:7, Psalm 19:1) and to give Him praise (Isaiah 43:21). Instead of putting Hashem in the center of their lives, seeking to give Him glory by obeying His commands from hearts of praise, the world lives for their own glory and praise, putting themselves in the place of Hashem as their object of worship, effectively becoming their own idols. Hashem has said, "My glory I will not give to another." (Isaiah 48:11). It has historically not gone well for those who gave themselves glory instead of Hashem. (Daniel 4: Nebuchadnezzar was made to eat grass like a beast for boasting in himself!)
Can we apply the commands for keeping separate from the Gentiles and their idols to these non-religious idols of our day such as money, fame, power, self-worship? As returning to obey Hashem required destruction of physical idols (i.e., Jeroboam's golden calves atop the high places), does modern-day obedience to these commands include uprooting these idols from our hearts and lives?