I haven't worked through all the etymological dictionaries yet so the connection might be obvious, (Jastrow and Klein don't seem to make it explicitly) but I am looking for discussion which connects the idea of being m'tzuyan (noteworthy or remarkable) and Tziyon. The word is questioned here (53rd gate) but no answer is given.
Specifically, I would think that such a connection would be useful in a discussion of the unique identity of Bnei Yisrael when the tribes settled in Goshen and were "metzuyanim" (or metzuyanin) there. This is explained as being "distinguishable," quantified by some commentators as retaining names, food and practices which defined them as a distinct son-of-Israel culture. One could then tie this homiletically to a lesson about retaining a connection to Tziyon.