How is the Book of Jubilees regarded by Orthodox Jewry (I'm not asking if we believe it existed, but if we hold any of the information in it to be accurate).
Is it ever quoted by any of the commentators? Do they ever discuss it?
This Jewish Encyclopedia entry says that the book pushes a Sadducee viewpoint:
But it is especially upon the right observance of the Feast of Weeks that the Book of Jubilees lays stress, following the Sadducean practise in insisting that it be celebrated each year on the first day of the week in literal conformity with the words "the morrow after Sabbath" (ch. vi. 17-22; see Lev. xxiii. 15-16). It was to take place on the 15th of Siwan. It was celebrated in heaven from the days of Creation until God ordained it to Noah. On that day God made the covenant with Abraham between pieces of sacrificial beasts, as mentioned in Gen. xv., while Abraham offered the first-fruits of his tillage with other sacrifices (ch. xiv. 10-20, xv. 1-9; see Charles, l.c. p. 106, notes). Celebrated, also, by Abraham, as the Feast of the Covenant of Circumcision (ch. xv. 3), and by Isaac (who was born on the 15th of Siwan; ch. xvi. 13) and Jacob (ch. xxii. 1, xxix. 6, xliv. 3), the Feast of Weeks was renewed by Moses for all generations as the Feast of the Covenant of Sinai (ch. vi. 19).
There is a short account of the history of the book here.