An answer to your second question can be brought from HaRav Elimelech Biederman's Torah Wellsprings (Parshas Vayishlach 5782).
He first brings the Daas Zekeinim as mentioned by @Shalom. However he then goes on to add the following:
Yaakov said (32:11):
כי במקלי עברתי את הירדן הזה ועתה הייתי לשתי מחנות
"I crossed this Yarden with my staff, and now I have become two camps."
Reb Chaim Volozhiner zt'l explains that also in this pasuk Yaakov is lamenting that he lost his bitachon. ,כי במקלי עברתי את הירדן הזה Yaakov said, "I used to have bitachon, and with my firm trust in Hashem, I put my staff in the Yarden, and the waters split.1 ועתה הייתי לשתי מחנות , but now I've divided my camp into two groups, as I am afraid that Eisav might attack one of them."
The Riv'a (from the Baalei HaTosfos) teaches that Yaakov lost his protection because of his fear. Hashem promised Yaakov that he would protect him. As it states (Bereishis 28:15) ושמרתיך בכל אשר תלך , "I will watch over you wherever you will go." But since Yaakov was afraid of Eisav, he lost his protection. As it states (32:26), ותקע כף ירך יעקב בהאבקו עמו "Yaakov's thigh was dislodged when he wrestled with [the malach]."
The Riv'a adds, "This also happened to Moshe. Hashem told him, כי אהיה עמך , 'I will
be with you,' yet he was injured at the hotel. This happened because he was afraid of Pharaoh, as he said, שלח נא ביד תשלח , 'Send someone else…'"2
1 The Degel Machaneh Efraim writes, "My grandfather (the Baal Shem Tov zt'l) said that he once crossed the Dnieper River without using Hashem's names. He placed his belt on the water, and he said that with immense emunah he crossed the river. This can be the translation of כי במקלי עברתי … that Yaakov crossed the Yarden with his immense emunah."
2 The Seforno explains that as long as Yaakov Avinu was thinking about Hashem, he was protected. The moment he lost focus, the malach was able to smite him on the thigh.
The Seforno writes, "Because of Yaakov's constant deveikus to Hashem in his thoughts and in his speech, the malach couldn’t harm him. But when the malach told him about the nation's future sins … ( הודיעו החטא העתיד במדריכי עמו ) this upset Yaakov, his deveikus ceased, and [that's when the angel hit him and] his thigh was dislodged…"