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There are a couple of indirect references in the Bavli: Rav advised his son not to take drugs habitually (Pesachim 113a). Rabbi Judah son of Rabbi Hiyya compared the drugs of humans to the drugs of HASHEM: "When a man administers a drug to another it may be beneficial to one limb but injurious to another, but with the Holy One, blessed be He, it is not so: ...

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