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Before nightfall at the start of 15 Nisan, Chametz is just like any other prohibited food in terms of nullification in mixtures (ShA OC 447:2, cf. YD 102:4) so regular rules like 1:60 and Ta'am Lifgam would apply. From that point until the end of Pesach it is never nullified in a mixture and forbids one from deriving any benefit from the mixture (OC 447:1). ...



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