So, for instance, one could say that the nekudot over the word "kissed" in the verse in which Esau kissed Jacob suggest that Esau tried to bite Jacob because the line of dots looks like bite marks. What are some examples like that which focus on the appearance of letters, words, or parts of words?
Why is the leg of the gimmel sticking towards the dalet? Because the "gomel" - bestower- of kindness runs after the "dalim" - downtrodden. Why is the leg of the dalet straight against the gimmel? To make himself available (and not need the benevolent benefactor to chase after him - Rashi). And why is the dalet facing away from the gimmel? To give to him in privacy in order to not embarrass him.
Why is the kuf turned away from the reish? Hashem (the Holy one - kuf represents Kadosh, see Gemara there) says "I cannot bear to look at the rasha (evil one). And why is the crown of the kuf facing the reish? Hashem says "If he returns, I wil give him a crown like Mine." And why is the leg of the kuf hanging (unattached)? So that if he returns, he can go in through that opening (which faces the reish).
See there for much more of the aleph beis.
Thank you! Also, apparently, bMenachot 29b:
R. Ashi said, I have observed that scribes who are most particular add a vertical stroke to the roof of the letter heth,and suspend the [inner] leg of the letter he. They add a vertical stroke to the roof of the letter heth, signifying thereby that He lives in the heights of the world. (Soncino translation here).