A good deal of ink has been spilled in the past century regarding the permissibility and appropriateness of American Jews celebrating Thanksgiving.
For the most part, Ashkenazim are split, with some big name 20th Century rabbis giving it the OK, and in some cases celebrating it themselves, while some still tend to just pretend it doesn't exist (although not with the same negativity generally directed at certain other non-Jewish holidays).
What about Sepharadim? I know that the Spanish-Portuguese Jewish community in the U.S. has a strong tradition to observe and celebrate Thanksgiving, dating back to the founding of the nation. But what about everyone else? Is there affirmation that Thanksgiving is a worthy holiday to observe? Is there opposition to it? Is there a more neutral response? Is there some mixture of the above like there is among Ashkenazim?